悬臂框架结构设计方案的分析比较

通过一个设计实例，介绍了工程设计中悬臂框架结构常用的处理措施；计算表明，在悬臂端设置端柱的方法是切实可行而有效的。     

钢-混凝土连续组合梁桥的理论分析和试验研究

根据完全剪力连接的连续组合梁桥的构造特点及各部分受力机理,做出合理假设,提出分层平面框架计算模型该计算模型用于沈阳市东西快速干道工程某段连续组合梁桥,计算值与静载试验实测值非常接近,证明了本计算模型用于钢-混凝土连续组合梁桥正确实用的.     

放射治疗剂量分布的Monte Carlo模拟

利用Monte Carlo方法模拟放射治疗剂量分布,改写现有的放射治疗软件DPM,并进行剂量计算。与图形处理方便的Matlab软件相结合,给出直观的显示结果。该方法是一个很有前景的研究方向,因为它既可以获得很快的仿真速度,又能得到直观的仿真结果图形。运行结果表明剂量计算能在1min之内完成,计算速度和精度满足要求。该方法对于提高放射治疗水平具有重要的指导意义和应用价值。     

Web-Based Information Extraction Technology

Information extraction techniques on the Web are the current research hotspot. Now many information extraction techniques based on different principles have appeared and have different capabilities. We classify the existing information extraction techniques by the principle of information extraction and analyze the methods and principles of semantic information adding, schema defining,rule expression, semantic items locating and object locating in the approaches. Based on the above survey and analysis,several open problems are discussed.     

国家自然科学基金面上项目资助额的地区分布规律

本文讨论了国家自然科学基金面上项目资助额的地区分布特点,发现基金面上项目资助额的地区分布与博士生人数的地区分布有很大的相关性,从而可以看出国家自然科学基金的资助在很大程度上取决于申请者所在地区具有的科研和教育水平。     

激光诱导化学气相合成纳米微粉的物理化学模型

针对激光低压化学气相合成纳米微粉材料的过程建立了物理化学统一模型,其中包括气体分子动力学、化学反应热力学和流体动力学三部分.分别介绍了模型的基本假设、基本公式及主要结论.描述了反应物分子的热运动状态,提出了激光强度阈值的预测方法,给出了生成物颗粒的成核速率、生长速率和最终粒径.模型对进一步揭示纳米微粉生成过程的物理化学机制,寻找宏观工艺参量对微观合成过程及所制备纳米微粉性质的影响规律有实际意义.     

一个可靠指标计算公式的误差分析

对美国桥梁设计规范中计算可靠指标的一个公式进行分析,认为该公式是近似的,并指出了其近似的原因。分别采用该公式和蒙特卡罗法计算可靠指标,计算结果表明该公式的误差高达30%,远远超出工程容许范围。因此在工程上应用该公式进行可靠指标计算是不合适的。     

Improving the thermal stability of lactate oxidase by directed evolution

Lactate oxidase is used in biosensors to measure the concentration of lactate in the blood and other body fluids. Increasing the thermostability of lactate oxidase can significantly prolong the lifetime of these biosensors. We have previously obtained a variant of lactate oxidase from Aerococcus viridans with two mutations (E160G/V198I) that is significantly more thermostable than the wild-type enzyme. Here we have attempted to further improve the thermostability of E160G/V198I lactate oxidase using directed evolution. We made a mutant lactate oxidase gene library by applying error-prone PCR and DNA shuffling, and screened for thermostable mutant lactate oxidase using a plate-based assay. After three rounds of screening we obtained a thermostable mutant lactate oxidase, which has six mutations (E160G/V198I/G36S/T103S/A232S/F277Y). The half-life of this lactate oxidase at 70 °C was about 2 times that of E160G/V198I and about 36 times that of the wild-type enzyme. The amino acid mutation process suggests that the combined neutral mutations are important in protein evolution. Received 15 September 2006; received after revision 21 October 2006; accepted 2 November 2006     

Forecast accuracy after pretesting with an application to the stock market

In econometrics, as a rule, the same data set is used to select the model and, conditional on the selected model, to forecast. However, one typically reports the properties of the (conditional) forecast, ignoring the fact that its properties are affected by the model selection (pretesting). This is wrong, and in this paper we show that the error can be substantial. We obtain explicit expressions for this error. To illustrate the theory we consider a regression approach to stock market forecasting, and show that the standard predictions ignoring pretesting are much less robust than naive econometrics might suggest. We also propose a forecast procedure based on the ‘neutral Laplace estimator’, which leads to an improvement over standard model selection procedures. Copyright © 2004 John Wiley & Sons, Ltd.     

南淝河水质S-P模型参数K1、K2的估值

对南淝河河流水质S-P模型中碳化BOD衰减系数K1和大气复氧系数K2分段进行了估值.根据实验测定数据,用最小二乘法、图解法和两点法等3种方法对K1进行了估值,应用公式估算法对K2进行了估值,并对估值的结果与南淝河的有机污染状况进行了对比和分析,从而为模型提供准确的参数值,也为南淝河的水污染控制和水质规划提供有益的借鉴.